Supplementing vitamin D3 and K2 can help promote the normal process of bone building and support cardiovascular function.
While vitamin D has long been known to assist calcium absorption, it is vitamin K, through its carboxylation of osteocalcin, which guides this calcium to bones and prevents their absorption into organs, joint spaces and arteries. Vitamin K occurs in 3 main forms: K1 (phylloquinone), derived from foods such as green leafy vegetables, K2 (menaquinone) which originates from bacteria; a third form, K3 (menadione), is a synthetic analogue. Numerous studies have shown that vitamin K2 is the more bioavailable form of the nutrient, and more powerfully influences bone building than K1. There are two forms of vitamin K2 commonly used in supplements: MK-4 and MK-7. The MK-7 form has been shown to have six times the activity of MK-4 in the blood. MK-7 has also been found to remain in the blood approximately nine times as long as the MK-4 (8 hours versus 72 hours), making it the optimal form of K2 for health.
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